Jean Bruno
All of the body's tissues and organs depend on blood arteries to carry oxygen and nutrients to them. The blood-brain barrier, a special property of the blood arteries that vascularize the Central Nervous System (CNS), enables these vessels to tightly control the transit of ions, chemicals, and cells between the blood and the brain. Correct neuronal function is enabled by the careful regulation of CNS homeostasis, which also safeguards neural tissue from toxins and infections. Alterations to these barrier qualities play a significant role in the pathophysiology and development of many neurological illnesses. The Endothelial Cells (ECs), which make up the blood vessel walls, have a variety of physical, transport, and metabolic characteristics that help to coordinate the physiological barrier.