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Artigo de Pesquisa

Two-year Assessment of the Efficacy and Safety of Ocrelizumab in Switching Patients from Other Disease Modifying Therapies

Terzi Murat, Boz Cavit, Demir Caner Feyzi, Cilingir Vedat, Helvaci Elif Merve

Objective: To evaluate the efficacy and safety of OCR in a real-world setting.
Methods: Clinical data for patients aged ≥ 18 years wi..Veja mais»

Artigo de Pesquisa

Regulation of the Human Delta-Opioid Receptor by Alkaloids: Different Roles of Arrestins

Elise Camacho, Benjamin Aguila, Nicolas Elie, Jana Sopkova, Caroline Marte, Audrey Davis, Cédric Lecoutey and Stéphane Allouche

Study background: We previously revealed that the arrestin 2 was differentially involved in the regulation of the human delta opioid receptor (hDOR) by peptidic and alkaloid ago..Veja mais»

Artigo de Pesquisa

Towards Consensus on the Reporting of Core Outcome Domains in Total Joint Replacement Clinical Trials: The Derivation of the Preliminary Core Outcome Domain Set

Jasvinder A Singh and Michael Dohm

Background: There is no consensus on how to report total joint replacement (TJR) trials. To our knowledge, core outcome domains for TJR clinical trials have not..Veja mais»

Resumos

The decision-making process in orthodontics: To extract or not to extract?

Omar El Bayoumy

The major consideration in this important decision relates to management of crowding/ protrusion and the possibility of camouflage for skeletal problems. Crowding/Protrusion. If..Veja mais»

Artigo de Pesquisa

A Single-Site, Investigator Initiated Open-Label Trial of Acthar® Gel (Repository Corticotropin Injection) a naturally sourced complex mixture of adrenocorticotropic hormone analogs and other pituitary peptides, in Subjects with Severely active Ankylosing Spondylitis (AS)

Joshua P. June

Ankylosing spondylitis (AS), is a chronic inflammatory arthritis of the spine which affects approximately 19 million people worldwide. It is defined by axial skeleton radiograph..Veja mais»