It's past time to figure out how comorbidities contribute to | 89039

Jornal Internacional de Pesquisa Colaborativa em Medicina Interna e Saúde Pública

ISSN - 1840-4529


It's past time to figure out how comorbidities contribute to the severity of COVID-19.

George Brown

The introduction of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from China has put human lives in jeopardy. Asymptomatic, mild, or severe pneumonia-like symptoms characterise Coronavirus Disease 2019 (COVID-19). COVID-19 people with diabetes, COPD, CVD, hypertension, cancer, HIV, and other comorbidities may face a life-threatening scenario. To enter the cell, SARS-CoV-2 uses ACE-2 receptors present on the surface of the host cell. Certain comorbidities are linked to increased ACE-2 receptor expression and proprotein convertase release, which aids viral entrance into host cells. The COVID-19 patient enters a vicious infectious loop of life as a result of the comorbidities, which are strongly linked to severe morbidity and mortality. Individuals with comorbid conditions must take extra precautions and be managed carefully. In this study, we concentrated on the impact of common morbidities in COVID-19 patients and reviewed therapy methods in light of recent developments. We discovered few materials describing the relationship between COVID-19 and comorbidities; nonetheless, this review defines the broader spectrum of comorbidities that COVID-19 patients face.